Research Grants

With the support of our SDS families and generous supporters, Shwachman Diamond Syndrome Foundation has funded the following projects in the United States and other countries. SDS is a very rare disease, we are grateful to those researchers who are willing to give their time and expertise to help those living with SDS.

If you are a researcher interested in submitting a grant request, please email info@shwachman-diamond.org.

Year Principal Investigator Project Title
2023 Akiko Shimamura, MD, PhD Improving Surveillance for leukemia risk in SDS
2022 Professor Alan Warren SDS Drug Discovery
2020 Garry Tobin, MD Diabetes Study
2016 Marc Raaijmakers,MD, PhD
Erasmus Medical Center, Netherlands		 “Reconstructing” Leukemogenesis in Shwachman Diamond Syndrome
2016 Seth Corey, MD Identification of Cooperating Genes in the Transformation of SDS to MDS/ AML in the Zebrafish Model that Phenocopies Human SDS
2015 Seth Corey, MD Identification of Cooperating Genes in the Transformation of SDS to MDS/ AML in the Zebrafish Model that Phenocopies Human SDS
2015 Allison Bertuch, MD, PhD Why are Shwachman-Diamond Syndrome Cells Hypersensitive to y-irradiation?
2014 Johnson Liu, MD SBDS Gene Expression Levels and Hematopoietic Defect in Shwachman-Diamond Syndrome: Groundwork and Application for Gene Therapy
2011 Paul de Figueiredo, PhD and Akiko Shimamura, MD, PhD Drug screen to show that HDAC (histone deacetylase) inhibitors will improve growth of Sdo1 deficient yeast cells
2010 Paul de Figueiredo, PhD Small molecule therapeutic approaches to SDS
2008 Akiko Shimamura, MD, PhD
Fred Hutchinson Cancer Research Center		 North American Shwachman-Diamond Syndrome Registry
2008 Nicholas Trede, MD
University of Utah		 Genetic analysis of Ceylon, a Zebrafish mutant with a genetically heritable SDS-like birth defect
2007 Akiko Shimamura, MD, PhD The Human SDS protein, SBDS, associates with Ribosomal RNA
2006 David Pearce, MD
University of Rochester		 Functional characteristics of sdo1p/SBDS
2006 E. Nicolis, MD
University Hospital of Vernon, Verona, Italy		 SBDS mRNA expression in peripheral blood leukocytes
2006 Peter Durle, MD
Hospital for Sick Children and University of Toronto		 SBDS protein expression in peripheral blood leukocytes
2005 Yigal Dror, MD
Hospital for Sick Children and University of Toronto		 Identification of Genes involved in Marrow Failure and Malignant Myeloid Transformation by Gene Expression Analysis of Bone Marrows from Patients with Shwachman-Diamond syndrome and other inherited Marrow Failure Syndromes
2004 Johnson Liu, MD
Mount Sini School of Medicine		 Hematopoietic Defect in Shwachman-Diamond Syndrome Knockdown and Overexpression of SBDS.

E-mail info@shwachman-diamond.org if interested in applying for a research grant.